PGXL had a couple of posters up at the Association of American Pathology annual meeting. The team took a look at CYP2D6 and CYP2D7 hybridization, and noted a new CYP3A4 haplotype resulting in diminished drug metabolism. The results of those studies will be used to keep the PGXL interpretive report as sharp as possible.
DOWNLOAD “Allele Frequency of Two Previously Unreported Cytochrome P450 3A Haplotypes”
DOWNLOAD “A Practical Approach to Genotyping CYP2D6-CYP2D7 Hybrid Alleles Using TaqMan”